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The passing on of genetic diseases from parents to children has always been a serious problem. Since 1990, it has been possible to do genetic testing on embryos before implantation in the uterus of the woman who wants to have a child. The method is called Preimplantation Genetic Diagnosis and is now a powerful tool for couples facing the increased likelihood of passing on a genetic disease to their children. Thousands of healthy children have been born worldwide due to the availability of this method.
Preimplantation genetic diagnosis is divided into two categories:
- diagnosed genetic diseases
- testing associated with chromosomal changes
Since it has been possible to diagnose genetic diseases, couples where each partner has a specific genetic disease can benefit (e.g., Type a and b Thalassaemia, or cystic fibrosis).
Screening for chromosomal alterations relates to numerical chromosome changes and structural abnormalities. This is a very important test, since it is known that the chances for chromosomal changes (e.g. Down’s Syndrome) increase with the woman’s age.
However, there are cases where changes in chromosome structure (inversion or translocation of chromosome material) do not depend on age. There are rare cases of couples where one or both partners contribute a chromosomal change (not necessarily the same). This change, may lead to recurrent miscarriages or repeated unsuccessful IVF attempts.
Preimplantation Genetic Diagnosis has been applied clinically for several years with very good results. Experience has shown that a successful programme of Preimplantation Genetic Diagnosis requires the harmonious cooperation of many specialties, such as doctors, clinical embryologists, psychologists and geneticists. At the same time, genetic counselling provided to the couple by specialists plays a particularly important role.
The contribution of genetic counselling, research and clinical documentation is considered indispensable in assisted reproductive technology and can demonstrably and accurately identify the probability of a couple having a healthy child using the process of pre-implantation genetic diagnosis.
to bare in mind
During PGS biopsy, the embryologist is able to determine the sex of the embryos. However, according to the legislation of several countries, clinics are not allowed to select the embryos to transfer based on desired sex, unless there is a sex-related inherited disease in the family. These are only a few places where sex selection is allowed, so get in touch with us for advice, if this is what you are looking for.
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After booking your treatment, we will make you a few suggestions on travel packages. You can decide whether you would like to go ahead and get one of those. Travel packages are paid to Redia in full.
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